Uterine prolapse appears to be a collagen–related problem that often runs in families and is more common in fair-skinned individuals, especially redheads. Without some form of intervention, prolapses do tend to worsen over time.

In the last decade, several surgical techniques have become available to suspend the uterus—including laparoscopic suspension—thus "curing" the prolapse without removing the uterus.

Pessaries are mechanical devices that come in many different shapes and sizes that are worn in the vagina to help keep the uterus and cervix in place. They are especially useful during activities that are associated with increased intra-abdominal pressure, such as lifting or aerobics, which tend to push the uterus further out. It is both an art and a science to fit them correctly, and many gynecologists have limited experience with them.

When the prolapse is mild (the cervix is low in the vagina but not protruding from the opening), strengthening the pelvic floor muscles with Kegel's exercises can sometimes prevent its progression.